Computation, Modeling & Signal Processing
Credit: Peter Allen
  1. research

Computation, Modeling & Signal Processing research topics include: neuroengineering to map and modify neural signaling; quantitative mechanobiology to reveal how physical forces and changes in the mechanics of cells and their environment drives cell signaling and responses; biological dynamics to describe and understand time varying biological systems; and the development of enabling methods such as quantitative image processing, machine learning and signal processing algorithms.

Affiliated Researchers

Marley Dewey

Assistant Professor of Bioengineering
The Dewey Lab engineers biomaterials with extracellular vesicles towards skeletal repair. Specifically, we examine a new class of extracellular vesicle residing in the extracellular matrix, termed matrix-bound nanovesicles. Using these tools we answer basic science questions and create translational therapies related to bone cancer, improving bone repair, preventing bone infection, and repairing coral reefs.
Cell, Tissue & Device Engineering
Computation, Modeling & Signal Processing

Siddharth Dey

Associate Professor of Bioengineering
Associate Professor of Chemical Engineering
The goal of our lab is to develop novel single-cell sequencing technologies to understand how variability in the epigenome regulates gene expression heterogeneity and cell fate decisions.
Synthetic & Systems Biology
Cell, Tissue & Device Engineering
Computation, Modeling & Signal Processing

Dorit Hanein

Professor of Bioengineering
Professor of Chemistry and Biochemistry
The Hanein Lab is exploring the structural functional complexities of the macromolecular machines that drive our biological processes—this includes imaging them in three-dimension and high resolution while at work in isolation, as well as within cells, organoids and tissues.
Computation, Modeling & Signal Processing
Synthetic & Systems Biology
Cell, Tissue & Device Engineering

Arnab Mukherjee

Assistant Professor of Bioengineering
Assistant Professor of Chemical Engineering
Our research focuses on engineering genetic reporters for imaging what we think of as the "dark matter" of biology - living systems that cannot be readily imaged using existing reporter gene techniques.
Synthetic & Systems Biology
Computation, Modeling & Signal Processing

Michelle O'Malley

Professor of Bioengineering
Professor of Chemical Engineering
Scholle Chair in Chemical Engineering
Genetic engineering and synthetic biology of non-model microorganisms.
Synthetic & Systems Biology
Computation, Modeling & Signal Processing

Kevin Plaxco

Professor of Chemistry & Biochemistry
Professor of Bioengineering
Biomolecular Science and Engineering Program
In-vivo molecular measurements, anyone?
Computation, Modeling & Signal Processing
Synthetic & Systems Biology
Cell, Tissue & Device Engineering

Beth L. Pruitt

Professor and Chair of Bioengineering
Professor of Mechanical Engineering
Director, NSF Research Training Program in Data Driven Biology
Director, NIH T32 Training Program in Quantitative Mechanobiology
Biomolecular Science and Engineering Program
The Pruitt Lab studies how mechanics mediates biological signaling using microtechnologies for cellular mechanobiology and mechanical measurements.
Cell, Tissue & Device Engineering
Computation, Modeling & Signal Processing

Ryan Stowers

Assistant Professor of Mechanical Engineering
Assistant Professor of Mechanical Engineering
Engineering biomaterials to probe questions in mechanobiology.
Cell, Tissue & Device Engineering
Computation, Modeling & Signal Processing

Yon Visell

Associate Professor of Bioengineering, and of Electrical and Computer Engineering
Media Arts and Technology Graduate Program
Mechanical Engineering
Haptics, Robotics, Tactile Sensing, Soft Electronics, Soft Robotics, Bioinspired Systems, Computational Acoustics
Computation, Modeling & Signal Processing
Cell, Tissue & Device Engineering