Kun Zhang, Ph.D. Professor Department of Bioengineering University of California, San Diego Title: Constructing Single-Cell Maps of Human Organs
CBE SEMINAR (Zoom)
This CBE Seminar will be hosted online via Zoom. RSVP to receive the zoom link by emailing info@bioengineering.ucsb.edu.
Zoom will open after the host has joined at the start of each seminar. You can ask questions through the chat forum and by raising your "hand" and the speaker will call on you.
Speaker
Kun Zhang, Ph.D.
Professor
Department of Bioengineering
University of California, San Diego
Faculty Host
Siddharth Dey
11:00 am in Bldg. ESB Room # 2001
Title: Constructing Single-Cell Maps of Human Organs
Abstract
Detailed characterization of the cell types comprising the highly complex human organs is essential to understanding their functions. Such tasks require highly scalable experimental approaches to examine multiple aspects of the molecular state of individual cells, registering cells to 3D coordinates, as well as the computational integration to produce unified cell state annotations and interpretation with biological and clinical relevance. To this end, we have established experimental platforms and computational pipelines for constructing 3D single-cell maps for human adult organs. In this talk I will present our recent progress constructing a reference cell atlas for human kidney.
BIO
Kun Zhang is the Leo and Trude Szilard Chancellor's Endowed Chair Professor, and Chairman of the Bioengineering Department at University of California, San Diego (UCSD). He received his B.S. and M.S. in Biophysics from Fudan University China in 1996 and 1999, and a Ph.D. degree from UT-Houston MD Anderson Cancer Center in 2003. After a post-doctoral training at Harvard Medical School, he joined the faculty at UCSD Bioengineering in 2007. His area of expertise is molecular engineering and biotechnology, with a specialization on genomics, epigenomics and single-cell sequencing. He pioneered the development of multiple methods on target genome and epigenome sequencing, single-cell genome sequencing, single-nucleus RNA sequencing, as well as single-cell multi-omics sequencing. He is leading multiple NIH funded center projects on constructing single-cell atlases for major human organs. He has been on the list of Web of Science highly cited researchers since 2019, based on the number of publications with citations that rank among the top 1% in the field. He has been active in technology commercialization and in 2015 co-founded Singlera Genomics, a UCSD spinoff that focuses on non-invasive early detection of cancer in blood. He was named as a Rising New Investigator by Genome Technology in 2007, and received the CBIS Young Investigator award in 2018. He was elected as a Fellow of the American Institute for Medical and Biological Engineering in 2017.
