Events

Mellichamp Lecture: Professor Michael B. Elowitz, California Institute of Technology, Mon., April 23, 2018 @ 2:30pm

Monday, April 23, 2018, Mosher House
Professor Michael B. Elowitz, California Institute of Technology, will be joining us on April 23, 2018 at 2:30 PM for the fourth annual Mellichamp Lecture in Systems Biology and Bioengineering
 
The Duncan and Suzanne Mellichamp Lecture in Systems Biology and Bioengineering 
 

Communication and computation in mammalian cells


Michael B. Elowitz 

Professor of Biology and Bioengineering; Investigator, Howard Hughes Medical Institute; Executive Officer for Biological Engineering,  California Institute of Technology 

 

April 23, 2018

2:30 PM-5:00 PM

Mosher-Alumni Hall

Circuits of interacting proteins provide key functions in living cells. We have been developing a ‘build-to-understand’ approach to this problem, reconstructing or re-wiring these pathways using synthetic biology approaches, and analyzing their dynamic behaviors at the level of individual cells. In this talk, I will discuss new work showing how natural and synthetic protein circuits provide computational capabilities to mammalian cells. One focus will be on communication circuit architectures in which distinct ligand and receptor variants interact promiscuously with one another. This architecture can enable programmable computations that allow cells to respond to different ligand environments or recognize distinct messages from other cells.

Introductions 2:30
Lecture 3:00 
Reception 4:00