Events

CBE/ENGR 225 Faculty Seminar: Rachel Segalman, Ph.D. Edward Noble Kramer Professor Professor and Chair in Department of Chemical Engineering Professor in Department of Materials University of California, Santa Barbara

Tuesday, April 12th, 4pm, in Bldg. ESB Room #2001

Rachel A. Segalman, Ph.D.

Edward Noble Kramer Professor

Professor and Chair in Department of Chemical Engineering

Professor in Department of Materials

 

University of California, Santa Barbara

Tuesday, April 12, 2016

 

2:00 pm

ESB, Room #2001

*Cookies and Coffee will be provided*

Sequence: Where Polymer Physics Meets Polypeptoids

Chain shape and monomer sequence are two handles that affect polymer properties and selfassembly;

however, it is difficult to control these handles in conventional synthetic polymers without

also changing other factors, such as chemistry. Polypeptoids, a class of sequence-specific bioinspired

polymers, have a chain shape that can be tuned by the introduction of monomers with bulky chiral

aromatic side chains, allowing one to induce a helical conformation while preserving the chemical

nature of the side chains. Here, we examine the rigidity of polypeptoid helices using small angle

neutron scattering to measure the persistence length of both a helical and a non-helical peptoid chain.

Incorporation of these polypeptoids into block copolymers enables a systematic study of the effect of

chain shape on self-assembly while maintaining similar enthalpic interactions. Because both the

helical and non-helical peptoid blocks have similar flexibilities, it is shown that the strength of

segregation depends much more on monomer composition. These studies are a promising basis for

further examining the effect of monomer sequence control on block copolymer self-assembly. In this

talk, I will also discuss the use of this model system to understand the role of sequence on chain

collapse and globule formation in solution, polymer crystallization, and potential application as surface active agents for anti-fouling.